Silver nanoparticles cause complications in pregnant mice

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Silver nanoparticles cause complications in pregnant mice.

BACKGROUND Silver nanoparticles (AgNPs) have attracted much interest and have been used for antibacterial, antifungal, anticancer, and antiangiogenic applications because of their unique properties. The increased usage of AgNPs leads to a potential hazard to human health. However, the potential effects of AgNPs on animal models are not clear. This study was designed to investigate the potential...

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Blood toxicity of silver nanoparticles in Pregnant Wistar Rats

Background: Investigation of toxicity of silver nanoparticle, especxially blood toxicity, is necessary because this nanoparticle is used a lot in diffrerent parts of life and invironment. The aime of this is evaluation the effects of silver nanoparticles with different concentrations on blood cells pregnant Wistar rats. Materials and Methods: In this case control study, 30 pregnant rat wer...

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A Transfer of Silver Nanoparticles from Pregnant Rat to Offspring

SILVER NANOPARTICLES (SIZE 7.9 ± 0.95 nm, dosage: 250 mg/kg) were orally administered to pregnant rats. At 4 days after parturition, four pups were randomly selected (one pup from one dam) and silver level in liver, kidney, lung and brain was determined by ICP-MS and electron microscope. As results, silver nanoparticles highly accumulated in the tissues of the pups. Silver level in the treated ...

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Toxicity of Silver Nanoparticles in Aquatic Ecosystems: Salinity as the Main Cause in Reducing Toxicity

Background: In recent years, silver nanoparticles due to their antimicrobial properties, have formed about 56% of nanoparticles global production. Since the released nanoparticles ultimately enter water ecosystems, their maximum toxic effects are magnified in aquatic ecosystems. The aim of this study is to show how salinity can decrease the toxic effects of silver nanoparticles on exposed rai...

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blood toxicity of silver nanoparticles in pregnant wistar rats

background: investigation of toxicity of silver nanoparticle, especxially blood toxicity, is necessary because this nanoparticle is used a lot in diffrerent parts of life and invironment. the aime of this is evaluation the effects of silver nanoparticles with different concentrations on blood cells pregnant wistar rats. materials and methods: in this case control study, 30 pregnant rat were div...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2015

ISSN: 1178-2013

DOI: 10.2147/ijn.s95694